AQA A-Level Biology Paper 1, June 2023

Every question from AQA A-Level Biology Paper 1, June 2023 (7402): 10 questions, 91 marks, each with its mark scheme and topic.

Original question paper

  1. Question 1 5 marks

    Give three structural features found in all virus particles and describe the function of one, explain why viruses are acellular and non-living, and state why antibiotics are not effective against viruses.

    Biology · 3.2 Cells

  2. Question 2 8 marks

    Describe three ways the structure of chitin is similar to cellulose, explain one adaptation of the insect gas exchange surface, and explain the importance of the xylem being kept open as a continuous tube.

    Biology · 3.1 Biological molecules · 3.3 Organisms exchange substances with their environment

  3. Question 3 9 marks

    Analyze Plasmodium vivax cell structure, Golgi functions, phylogenetic evolution, calculate malaria case numbers, and explain the natural selection of malaria resistance in Africa.

    Biology · 3.2 Cells · 3.4 Genetic information, variation and relationships between organisms · 3.7 Genetics, populations, evolution and ecosystems (A-level only)

  4. Question 4 9 marks

    Explain how Clostridium difficile toxins damage ileum cells leading to reduced absorption and diarrhoea, analyze anti-toxin antibody levels in hospital patients, and describe protein digestion of antibodies.

    Biology · 3.1 Biological molecules · 3.2 Cells · 3.3 Organisms exchange substances with their environment · 3.4 Genetic information, variation and relationships between organisms

  5. Question 5 10 marks

    Investigate the use of cinnamon oil as an antimicrobial substance using agar plates, aseptic techniques, cylinder volume calculations, and analysis of clear zones.

    Practical skills · Required Practicals · Experimental design · Data analysis · AS practicals (1–6)

  6. Question 6 8 marks

    Define genome and proteome, evaluate early bacterial classification using flagella, suggest reasons for renaming species, and calculate image magnification.

    Biology · 3.4 Genetic information, variation and relationships between organisms

  7. Question 7 6 marks

    Analyze how carbon monoxide exposure affects the loading and unloading of oxygen by haemoglobin using a dissociation curve, and evaluate scientists' conclusions based on WHO recommendations and mathematical models.

    Biology · Practical skills · 3.3 Organisms exchange substances with their environment · Data analysis

  8. Question 8 10 marks

    Analyze the effects of the cancer-treating drug MiTMAB on cell division, enzyme inhibition, and cell culture growth using graphical and microscopic data.

    Biology · Practical skills · 3.2 Cells · 3.1 Biological molecules · 3.8 The control of gene expression (A-level only) · Data analysis

  9. Question 9 11 marks

    Evaluate an ELISA test for dengue fever involving monoclonal antibodies, diagnostic accuracy data, and physiological effects on tissue fluid return.

    Biology · 3.2 Cells · 3.3 Organisms exchange substances with their environment

  10. Question 10 15 marks

    Describe quaternary protein formation, DNA and chromosome structure, and other processes causing genetic variation.

    Biology · 3.1 Biological molecules · 3.4 Genetic information, variation and relationships between organisms

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