AQA GCSE Combined Science: Trilogy Biology Paper 2 (Higher), 2020: Question 1
9 marks · Standard Demand difficulty · Short Answer
Identify a DNA molecule, describe DNA structure and gene function, define genome, recognise an application of genome knowledge, and explain variation and natural selection using snail examples.
Practise this questionQuestion
Question text
01 This question is about DNA and genes.
01.1 Which diagram represents a DNA molecule?
[1 mark]
Tick ( ) one box.
01.2 Describe the structure of a DNA molecule.
[1 mark]
01.3 A gene is a small section of DNA on a chromosome.
Complete the sentences.
[2 marks]
A gene codes for a particular sequence of .
This sequence makes a specific 3 .
01.4 What is meant by the term genome?
[1 mark]
01.5 The complete human genome is now known.
Which important scientific advance was made using knowledge of the
human genome?
*02* [1 mark]
Tick ( ) one box.
Discovering antibiotic resistant bacteria
Finding more foods to eat from tropical forests
Tracing how aboriginal people spread across Australia
Working out when the last ice age ended4
A student found six different snails of one species in his garden.
Figure 1 shows the snails.
Figure 1
01.6 All the snails are different.
What scientific term describes differences in characteristics between individuals of
a species?
[1 mark]
01.7 A change in DNA has caused snail P to be very different from the other five snails.
Suggest why there might be an increasing number of snails similar to snail P in each
future generation.
[2 marks]
Mark scheme
Show the mark scheme
AO /
Question Answers Extra information Mark
Spec. Ref.
01.1 1 AO2
4.6.1.3
01.2 any one from: 1 AO1
• 2 strands / chains that are allow cross links between 2 4.6.1.3
twisted / coiled / spiralled strands / chains
• double helix
• (long) polymer
allow reference to nucleotides or
sugars, phosphates and bases
01.3 in this order only AO1
amino acids 1 4.6.1.3
protein allow polypeptide 1
01.4 all the genetic material (of an allow DNA / genes for genetic 1 AO1
organism) material 4.6.1.3
ignore chromosomes
01.5 tracing how aboriginal people 1 AO2
spread across Australia 4.6.1.3
01.6 variation – OMBINED SCIENCE:ignore genetic/environmentalTRILOGY– 1 – AO1
4.6.2.1
01.7 stronger / larger (shell) 1 AO2
4.6.2.2
(so) more likely to (survive and) 1
breed
or
(so) more likely to (survive and)
pass on genes
OR
(better) camouflaged (1)
(so) less likely to be eaten and
will breed more (1)
Total 9
How to answer it
DNA, Genes and Variation
Part (a) 01.1 – Which diagram represents a DNA molecule?
1 mark
✅ Correct answer
Tick the middle diagram. It shows the double helix shape of DNA.
💡 Key knowledge
- DNA is shaped like a twisted ladder.
- This structure is called a double helix.
- It consists of two strands coiled around each other.
🧠 Exam technique
For a 1-mark image question, choose the diagram that matches the standard textbook model of DNA. You do not need extra explanation unless asked.
❌ Common errors
- Picking the wrong shape because it “looks scientific”.
- Confusing DNA with a cell, chromosome, or molecule diagram that is not the double helix.
Part (b) 01.2 – Describe the structure of a DNA molecule
1 mark
✅ Correct answer
DNA is made of two strands twisted/coiled around each other to form a double helix.
💡 Key knowledge
- Accept: two strands, twisted, coiled, or spiralled.
- You could also mention DNA is a long polymer.
- Examiner note: references to cross-links between the two strands are allowed.
🧠 Exam technique
For 1 mark, one accurate statement is enough. The safest answer is to say “two strands twisted into a double helix”.
❌ Common errors
- Writing only “a helix” without saying it has two strands.
- Confusing DNA structure with the idea of genes or chromosomes.
- Giving very vague answers like “it is shaped like a ladder” without showing twisting.
Part (c) 01.3 – Complete the sentences about genes
2 marks
✅ Correct answers
A gene codes for a particular sequence of amino acids .
This sequence makes a specific protein .
💡 Key knowledge
- Genes are sections of DNA that contain instructions.
- The order is important: DNA → amino acids → protein.
- Accept polypeptide for protein.
🧠 Exam technique
Marks are awarded in the correct order. Even if you know the ideas, the answer must fit each blank properly.
❌ Common errors
- Writing “protein” in the first blank.
- Putting the words in the wrong order.
- Saying “a gene codes for a trait” instead of the required biological sequence.
Part (d) 01.4 – What is meant by the term genome?
1 mark
✅ Correct answer
The genome is all the genetic material of an organism.
💡 Key knowledge
- You may also see: all the DNA or all the genes.
- It refers to the complete set of genetic information.
🧠 Exam technique
Use the exact idea of whole genetic material. This is a definition question, so keep it precise.
❌ Common errors
- Saying chromosomes alone is enough.
- Giving a description of one gene instead of the whole organism’s genetic material.
Part (e) 01.5 – An important scientific advance using the human genome
1 mark
✅ Correct answer
Tracing how Aboriginal people spread across Australia
💡 Key knowledge
- Genome information can be used to study ancestry and population movement.
- This question expects the example from the mark scheme, not a random use of genome data.
🧠 Exam technique
When a question asks for one correct example, choose the option that directly uses DNA/genome comparisons for human history.
❌ Common errors
- Choosing an answer that sounds scientific but is unrelated to the genome.
- Thinking the human genome is mainly used for food, weather, or climate questions.
Part (f) 01.6 – What scientific term describes differences in characteristics between individuals of a species?
1 mark
✅ Correct answer
Variation
💡 Key knowledge
- Variation means individuals in a species are not all exactly the same.
- Differences can be inherited or caused by the environment.
🧠 Exam technique
This is a straight recall term. Give the exact scientific word.
❌ Common errors
- Writing a full explanation instead of the key term.
- Confusing variation with evolution or adaptation.
Part (g) 01.7 – Why might there be more snails like snail P in future generations?
2 marks
✅ Correct answer
Snail P may have a stronger/larger shell, so it is more likely to survive and breed.
Alternatively, it may be better camouflaged, so it is less likely to be eaten and will breed more.
💡 Key knowledge
- Useful traits help an organism survive.
- Organisms that survive are more likely to reproduce.
- They pass the helpful genes to their offspring.
🧠 Exam technique
To get both marks, link the feature of snail P to survival and then to breeding/passing on genes. This is the full explanation the examiner wants.
❌ Common errors
- Only describing snail P as different, without explaining why it becomes more common.
- Missing the key idea of survive → reproduce → pass on genes.
- Using vague language like “it is better” without saying why that helps.
📐 Quick answer structure for 2-mark biology explanations
- State the feature: stronger/larger shell or better camouflage.
- Explain the advantage: less likely to be eaten / more likely to survive.
- Finish with inheritance: more likely to breed and pass on the genes.
Overall examiner insight
💡 What the examiner rewards
- Accurate key terms: double helix, amino acids, protein, genome, variation.
- Clear links in explanations, especially in the snail question.
- Using the exact order required in fill-in-the-blank questions.
🧠 Best revision takeaway
Learn the simple chain:
DNA → gene → amino acid sequence → protein → characteristic
And for evolution questions:
variation → survival advantage → breeding → genes passed on
Topics
Biology · B6: Inheritance, Variation and Evolution
Question and mark scheme from the AQA GCSE Combined Science: Trilogy examination, Biology Paper 2 (Higher), 2020. QuestionVault is an independent revision resource; questions remain the copyright of the awarding body.