AQA A-Level Biology Paper 1, November 2021

Every question from AQA A-Level Biology Paper 1, November 2021 (7402): 10 questions, 91 marks, each with its mark scheme and topic.

Original question paper

  1. Question 1 8 marks

    Describe the induced-fit model of enzyme action, identify the substrate for ATP synthase to produce ATP, suggest a procedure to stop an enzyme reaction, and explain the effect of inorganic phosphate concentration on ATP concentration.

    Biology · Practical skills · 3.1 Biological molecules · Experimental design

  2. Question 2 11 marks

    Explain gas exchange mechanisms and adaptations in fish and mammals, including surface area to volume ratios, counter-current flow, and lung volume calculations.

    Biology · 3.3 Organisms exchange substances with their environment

  3. Question 3 7 marks

    Describe translation, explain how an amino acid replacement changes protein properties using a genetic code table, and complete codons/triplets for a substitution mutation.

    Biology · 3.4 Genetic information, variation and relationships between organisms · 3.8 The control of gene expression (A-level only)

  4. Question 4 6 marks

    Suggest improvements for a scientific drawing of dissected blood vessels, identify vessel types and features from a drawing, and state safety precautions for clearing away after a mammalian organ dissection.

    Biology · Practical skills · Required Practicals · 3.3 Organisms exchange substances with their environment · Experimental design · AS practicals (1–6)

  5. Question 5 10 marks

    Describe how to isolate chloroplasts from leaves, identify features of chloroplasts that synthesize proteins, calculate ratios of protein to chlorophyll, and explain the effects of iron deficiency on plant growth based on electron micrographs.

    Biology · Practical skills · 3.2 Cells · 3.5 Energy transfers in and between organisms (A-level only) · Data analysis · Experimental design

  6. Question 6 7 marks

    Calculate the rate of movement of centromeres during phase E from the graph and name the three phases of mitosis, describing the role of spindle fibres and chromosome behavior in each.

    Biology · 3.2 Cells

  7. Question 7 10 marks

    Explain the action and side effects of antibody-drug conjugates (ADCs) in cancer treatment, calculate an injection dosage, and evaluate drug testing methodology.

    Biology · Practical skills · 3.2 Cells · Experimental design · Data analysis

  8. Question 8 10 marks

    Describe triglyceride formation, identify fatty acid structures, evaluate experimental root growth data in Helianthus annuus populations, and explain species definition.

    Biology · Practical skills · 3.1 Biological molecules · 3.4 Genetic information, variation and relationships between organisms · 3.6 Organisms respond to changes in their internal and external environments (A-level only) · Data analysis · Uncertainty and evaluation

  9. Question 9 7 marks

    Complete Table 7 with ticks to show elemental composition, use Figure 11 to calculate generation time, and identify the supported model of DNA replication from experimental density results.

    Biology · 3.1 Biological molecules

  10. Question 10 15 marks

    Describe the structure of DNA, name and describe five ways substances can move across the cell-surface membrane, and contrast the structure of the two cells visible in the electron micrographs.

    Biology · 3.1 Biological molecules · 3.2 Cells

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