AQA A-Level Biology Paper 1, June 2025
Every question from AQA A-Level Biology Paper 1, June 2025 (7402): 10 questions, 91 marks, each with its mark scheme and topic.
- Question 1 6 marks
Explain the importance of emulsification and micelles in the digestion and absorption of lipids, and describe and explain the arrangement of phospholipids in the cell-surface membrane.
Biology · 3.1 Biological molecules · 3.2 Cells · 3.3 Organisms exchange substances with their environment
- Question 2 8 marks
Describe mRNA splicing and RNA polymerase action, identify activation energy from a reaction profile, and compare historical enzyme conclusions with the induced-fit model.
Biology · 3.1 Biological molecules · 3.4 Genetic information, variation and relationships between organisms
- Question 3 10 marks
Identify features of biological molecules, calculate a solution volume from a ratio, and explain competitive enzyme inhibition using experimental data.
Biology · Practical skills · 3.1 Biological molecules · Experimental design · Data analysis
- Question 4 6 marks
Name structures variable in prokaryotes, and select and justify appropriate types of microscopes for two given biological investigations using data on resolution and specimen dimensions.
Biology · Practical skills · 3.2 Cells · Experimental design
- Question 5 9 marks
Explain how carrier proteins, ATP hydrolysis, and gene expression affect pear vacuole volume and pH during ripening, including the effect of a respiratory inhibitor.
Biology · 3.1 Biological molecules · 3.2 Cells · 3.5 Energy transfers in and between organisms (A-level only) · 3.8 The control of gene expression (A-level only)
- Question 6 10 marks
Explain haemocyanin oxygen dissociation at different temperatures, describe colorimetric calibration curve production, calculate crab running distance from a graph, and evaluate a line of best fit.
Biology · Practical skills · 3.3 Organisms exchange substances with their environment · Experimental design · Data analysis · Uncertainty and evaluation
- Question 7 9 marks
Calculate sperm production from epithelial cells, draw a bar chart showing DNA mass during meiosis, illustrate chromosome division, and explain non-disjunction.
Biology · Practical skills · 3.2 Cells · 3.4 Genetic information, variation and relationships between organisms · Data analysis
- Question 8 11 marks
Explain antibiotic resistance in hospitals using natural selection, calculate and interpret Spearman rank correlation coefficient for plasmid length and copy number, calculate total plasmid length, and analyze plasmid replication and binary fission during population growth phases.
Biology · Practical skills · 3.2 Cells · 3.4 Genetic information, variation and relationships between organisms · Data analysis
- Question 9 7 marks
Identify cell organisation terms and chloroplast structures from micrographs, predict the effect on photosynthesis, and explain data regarding chlorophyll ratios and photosynthetic rate in mutant plants.
Biology · Practical skills · 3.2 Cells · 3.5 Energy transfers in and between organisms (A-level only) · Data analysis
- Question 10 15 marks
Describe translation roles of ribosomes, tRNA, and ATP; leaf adaptations for gas exchange; and the pathway of blood from a kidney to the coronary arteries.
Biology · 3.1 Biological molecules · 3.3 Organisms exchange substances with their environment · 3.4 Genetic information, variation and relationships between organisms