AQA AS Level Biology Paper 1, June 2024

Every question from AQA AS Level Biology Paper 1, June 2024 (7401): 9 questions, 75 marks, each with its mark scheme and topic.

Original question paper

  1. Question 1 6 marks

    Name structures in the human gas exchange system, match physiological processes and pathways to letters on an alveolus and blood vessel diagram, and describe and explain an adaptation of a single alveolus for gas exchange.

    Biology · 3.3 Organisms exchange substances with their environment

  2. Question 2 10 marks

    Complete a table on starch and dipeptide digestion, describe and explain a protein test, and calculate the maximum rate of an enzyme-controlled reaction using turnover number.

    Biology · Practical skills · 3.1 Biological molecules · 3.3 Organisms exchange substances with their environment · Data analysis

  3. Question 3 8 marks

    Describe virus replication, explain clear zones on a bacterial culture caused by a virus, predict the appearance of the petri dish after extended incubation, and identify/explain a stage of the cell cycle shown in a micrograph.

    Biology · 3.2 Cells

  4. Question 4 7 marks

    Complete a table showing DNA features in prokaryotic cells, nuclei and chloroplasts, then use a bar chart to calculate the percentage of deaths involving causal E. coli and identify an incorrect mathematical step, and finally choose the best method for decreasing the frequency of antibiotic-resistant bacteria in human populations.

    Biology · Practical skills · 3.1 Biological molecules · 3.4 Genetic information, variation and relationships between organisms · 3.3 Organisms exchange substances with their environment · Data analysis

  5. Question 5 11 marks

    Describe methods to measure plant heights and calculate a reliable mean, construct a histogram table, calculate the index of diversity using provided bee species data, and explain the difference in bee species richness between wild flower and wheat fields.

    Biology · Practical skills · 3.4 Genetic information, variation and relationships between organisms · Experimental design · Data analysis

  6. Question 6 8 marks

    Give two roles of phosphate ions, describe the effect of increased hydrogen ion concentration on plasma proteins, use a bar chart (Figure 7) to describe ion concentration patterns, and explain sodium ion transport mechanisms across cell membranes.

    Biology · 3.1 Biological molecules · 3.2 Cells

  7. Question 7 6 marks

    Complete Figure 8 to show a monoclonal antibody attached to a drug, label one structural feature, and evaluate the effectiveness of an antibody-drug complex (ADC) in treating Hodgkin lymphoma using clinical trial data.

    Biology · Practical skills · 3.2 Cells · Data analysis

  8. Question 8 9 marks

    Explain how a non-competitive inhibitor decreases the rate of an enzyme-controlled reaction, identify variables in an enzyme-substrate investigation, calculate reaction rate from a tangent on a casein concentration-time graph, and sketch a predicted curve at an optimum temperature.

    Biology · Practical skills · 3.1 Biological molecules · Experimental design · Data analysis

  9. Question 9 10 marks

    Analyze a passage on spontaneous DNA mutations, nucleotide changes, and the effects of ataxia telangiectasia (AT) enzyme deficiency through calculation, structural comparisons, and explanations of mutations and cell cycle control.

    Biology · 3.1 Biological molecules · 3.4 Genetic information, variation and relationships between organisms

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