AQA GCSE Combined Science: Trilogy Biology Paper 1 (Foundation), 2024: Question 3

9 marks · Low Demand difficulty · Short Answer

Identify components and functions of blood, name substances transported in blood, and evaluate advantages and disadvantages of blood donation and transfusion.

Practise this question

Question

The question page shows Figure 5, a labelled diagram of blood inside a rectangular field with many pale biconcave red blood cells, two larger shaded white blood cells with lobed nuclei, tiny clustered platelets, and surrounding plasma. Arrows labelled A, B, C and D point to different parts of the blood, followed by six sub-questions asking which letter is a white blood cell, which blood part causes clotting, to name two transported substances, to suggest why blood is removed from a vein not an artery, and to give one advantage and one disadvantage for both a patient receiving blood and a volunteer donating blood. The page includes tick boxes for multiple-choice parts and lined spaces for written answers, with marks of 1, 1, 2, 1, 2 and 2 shown for the sub-questions.
Question text

03 Figure 5 shows different parts of blood.

Figure 5

03.1 Which letter shows a white blood cell?

[1 mark]

Tick ( ) one box.

A B C D

03.2 Which part of the blood causes the blood to clot?

[1 mark]

Tick ( ) one box.

Plasma

Platelets

Red blood cells

03.3 Name two substances transported in the blood.

[2 marks]

Healthy people can volunteer to donate blood.

The donated blood is then given to patients who need the blood.

When a volunteer donates blood:

• the volunteer’s health is checked

• a needle is used to remove blood from a vein in the arm

• the volunteer rests for 15 minutes after the donation.

03.4 Suggest one reason why blood is removed from a vein and not from an artery.

[1 mark]

Patients may receive blood during a medical emergency.

Donating blood and receiving blood has risks.

03.5 Suggest one advantage and one disadvantage to a patient who receives blood.

[2 marks]

Advantage

Disadvantage

03.6 Suggest one advantage and one disadvantage to the volunteer who donates blood.

[2 marks]

Advantage

Disadvantage

Mark scheme

Show the mark scheme The mark scheme is presented in tables for Question 3 with columns for question number, answers, extra information, marks, and AO/specification reference. It gives 03.1 as C for the white blood cell, 03.2 as platelets for clotting, and 03.3 any two transported substances such as oxygen, hormones, urea, carbon dioxide, water, glucose, amino acids, fatty acids, glycerol, antibodies, lactic acid, minerals or vitamins, with related allowances noted. For 03.4 it credits reasons veins are used because blood is under lower pressure, bleeding is easier to stop, veins are easier to puncture or access, less painful, or blood flows smoothly; for 03.5 and 03.6 it lists acceptable advantages and disadvantages of receiving blood and donating blood, such as saving lives versus infection or rejection risk for recipients, and helping others versus pain, bruising, time, infection risk, or feeling unwell for donors. The total for Question 3 is 9 marks.

Question 3

AO /

Question Answers Extra information Mark

Spec. Ref.

03.1 C 1 AO1

4.2.2.3

AO /

Spec. Ref.

03.2 platelets 1 AO1

4.2.2.3

AO /

Spec. Ref.

03.3 any two from: 2 AO1

• oxygen 4.2.2.1

• hormones 4.2.2.3

• urea

• carbon dioxide

• water

• glucose allow sugar

• amino acids

• fatty acids

• glycerol

• antibodies

• lactic acid

• minerals

• vitamins

allow 2 named minerals /

vitamins / hormones / drugs for

2 marks

allow other correctly named

substances such as proteins

AO /

Spec. Ref.

03.4 any one from: allow converse if clearly 1 AO3

referring to arteries 4.2.2.2

• blood is under lower pressure

• easier to stop the bleeding allow less bleeding (after the

donation)

• easier to puncture the vein allow (veins) have thinner walls

• easier to access (vein / blood) allow (veins) are closer to the

surface (of the skin)

• less painful

• blood flows smoothly

10 ignore references to safety

ignore references to oxygenated

and deoxygenated blood

Question Answers Extra information Mark AO /

Spec. Ref.

03.5 (advantage) AO3

any one from: 1 4.2.2.3

• improved quality of life

• lives are saved or deaths are

reduced

• reduced anaemia

• restores blood levels ignore more blood unqualified

(following severe burns /

blood-loss)

(disadvantage)

any one from: 1

• risk of infection

• risk of rejection allow blood type must match

allow wrong blood type given

• allergic reaction

• bruising

ignore religion

AO /

Spec. Ref.

03.6 (advantage) AO3

any one from: 1 4.2.2.3

• (pleasure from) helping others allow feel good factor

or (happiness from) saving

lives

• reveal potential health allow examples such as HIV

problems

(disadvantage)

any one from: 1 11

• pain (when donating)

• risk of infection

• time (spent while donating)

• feeling unwell (after donation) allow dizzy / hot / sweating /

trembling / nauseous / fainting

• bruising (from the donation

site)

• reduced physical activity for allow fatigue

the rest of the day

• possibility of rebleeding

ignore religion

Total Question 3 9

How to answer it

Blood Components and Donation

What this question tests

You need to पहचान/identify parts of blood from a diagram, know what platelets do, recall substances transported by blood, and explain simple advantages/disadvantages of blood donation. Full marks come from using correct biology terms and giving one clear reason per 1-mark part.

Part 03.1 — Which letter shows a white blood cell?

✅ Correct answer

C

Mark point: 1 mark for the correct label.

💡 Key knowledge

  • White blood cells are larger and have an irregular nucleus.
  • Red blood cells are more numerous and look like pale discs.
  • Platelets are tiny cell fragments, shown as small dots.

🧠 Exam technique

  • Use the shape and size in the diagram, not just guesswork.
  • White blood cells often stand out because they are fewer and bigger.

❌ Common errors

  • Choosing a red blood cell because it is the most obvious structure.
  • Mixing up platelets with white blood cells.

Part 03.2 — Which part of the blood causes the blood to clot?

✅ Correct answer

Platelets

Mark point: 1 mark for naming platelets.

💡 Key knowledge

  • Platelets help blood clot at a wound.
  • Clotting helps prevent too much blood loss.

🧠 Exam technique

Write the exact biological term. “Blood cells” is too vague.

❌ Common errors

  • Saying plasma, because plasma carries many substances but does not clot blood.
  • Writing red blood cells.

Part 03.3 — Name two substances transported in the blood

✅ Correct answers

Any two from:

  • oxygen
  • hormones
  • urea
  • carbon dioxide
  • water
  • glucose
  • amino acids
  • fatty acids
  • glycerol
  • antibodies
  • lactic acid
  • minerals
  • vitamins

Mark point: 1 mark for each correct substance, up to 2 marks.

💡 Key knowledge

Blood is a transport system. It carries useful substances to cells and waste substances away from cells.

Accept sugar for glucose.

Other correctly named substances can also be accepted, such as proteins.

🧠 Exam technique

  • Give two different examples.
  • Use clear science vocabulary: oxygen , glucose , carbon dioxide .

❌ Common errors

  • Writing “food” or “nutrients” without naming a substance.
  • Repeating the same idea in different words.

Part 03.4 — Why is blood removed from a vein and not an artery?

✅ Correct answer

Any one from:

  • blood is under lower pressure
  • easier to stop the bleeding
  • easier to puncture the vein
  • easier to access (vein / blood)
  • less painful
  • blood flows smoothly

Mark point: 1 clear reason for using a vein.

💡 Key knowledge

  • Veins carry blood at lower pressure than arteries.
  • Veins are often closer to the skin surface and have thinner walls.

🧠 Exam technique

The question asks for one reason only. A short, direct answer is enough.

❌ Common errors

  • Talking about oxygenated vs deoxygenated blood — this is ignored.
  • Giving a safety explanation instead of a biology reason.

Part 03.5 — One advantage and one disadvantage to a patient who receives blood

✅ Correct answers

Advantage — any one from:

  • improved quality of life
  • lives are saved or deaths are reduced
  • reduced anaemia
  • restores blood levels after severe burns / blood loss

Disadvantage — any one from:

  • risk of infection
  • risk of rejection
  • allergic reaction
  • bruising

Mark point: 1 mark for one advantage and 1 mark for one disadvantage.

💡 Key knowledge

Blood transfusions can help replace blood quickly in emergencies, but they carry risks.

Blood type must match for safe transfusion; otherwise the wrong blood type may be given.

🧠 Exam technique

  • For the advantage, link the transfusion to helping the patient.
  • For the disadvantage, name a real medical risk.

❌ Common errors

  • Writing a vague statement like “it is good” or “it is bad”.
  • Repeating the same point for both advantage and disadvantage.

Part 03.6 — One advantage and one disadvantage to the volunteer who donates blood

✅ Correct answers

Advantage — any one from:

  • pleasure from helping others
  • happiness from saving lives
  • reveal potential health problems

Disadvantage — any one from:

  • pain when donating
  • risk of infection
  • time spent while donating
  • feeling unwell after donation
  • bruising from the donation site
  • reduced physical activity for the rest of the day
  • possibility of rebleeding

Mark point: 1 mark for one advantage and 1 mark for one disadvantage.

💡 Key knowledge

  • A donor may feel a “feel good” factor from helping others.
  • Some donors may be told about possible health problems, including examples such as HIV.
  • Common physical side effects include dizziness, nausea, sweating, trembling or fainting.

🧠 Exam technique

  • Give one clear social/emotional benefit or health benefit.
  • For the disadvantage, use a specific practical effect, not just “it is risky”.

❌ Common errors

  • Using religious reasons — ignored by the mark scheme.
  • Writing “pain” and “uncomfortable” as if they are two different marks.

Quick recap: how the marks were earned

💡 Core facts to memorise

  • White blood cell = C in the diagram.
  • Platelets cause clotting.
  • Blood transports substances such as oxygen and glucose.
  • Veins are used for donation because pressure is lower.
  • Transfusion benefits patients, but there is a risk of infection or rejection.
  • Donation can help others, but it may cause pain or bruising.

🧠 Top-mark strategy

  • For 1-mark questions, one correct biology word is enough.
  • For 2-mark questions, give two separate points.
  • Use exact terms from GCSE biology: platelets , vein , infection , rejection .

Topics

Biology · B2: Organisation

Question and mark scheme from the AQA GCSE Combined Science: Trilogy examination, Biology Paper 1 (Foundation), 2024. QuestionVault is an independent revision resource; questions remain the copyright of the awarding body.