AQA GCSE Combined Science: Trilogy Biology Paper 1 (Higher), June 2025

Every question from AQA GCSE Combined Science: Trilogy Biology Paper 1 (Higher), June 2025 (8464): 6 questions, 70 marks, each with its mark scheme and topic.

Original question paper

  1. Question 1 10 marks

    Identify structures and functions of the heart, explain the presence of mitochondria in heart muscle cells, and suggest symptoms and surgical risks related to a hole in the heart.

    Biology · B2: Organisation · B1: Cell Biology · B4: Bioenergetics

  2. Question 2 12 marks

    Explain the transmission of chickenpox, why antibiotics are ineffective, the composition and testing of vaccines, and how vaccination confers immunity against future infection.

    Biology · B3: Infection and Response

  3. Question 3 9 marks

    Analyze an investigation into the effect of light intensity and temperature on the rate of photosynthesis in pondweed using the inverse square law and collision theory.

    Biology · B4: Bioenergetics · B2: Organisation

  4. Question 4 10 marks

    Explain osmosis in potato tissue, analyze the effect of surface area on percentage mass increase, and describe modifications to investigate salt concentration.

    Biology · B1: Cell Biology

  5. Question 5 10 marks

    Answer questions on plant anaerobic respiration, identify and describe adaptations of palisade mesophyll, and describe the transport of water from the soil to the atmosphere.

    Biology · B2: Organisation · B4: Bioenergetics

  6. Question 6 19 marks

    Analyze microscopy of ciliated cells, calculate real cell size, explain anaemia's effect on muscle fatigue, calculate viable red blood cells produced from stem cells, and evaluate blood transfusion sources.

    Biology · B1: Cell Biology · B2: Organisation · B4: Bioenergetics

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